Azulfidine (Sulfasalazine)

Pronounced: SUL-fa-SAL-a-zeen

Azulfidine is used for:

Treating ulcerative colitis. It is also used to increase the time between attacks of ulcerative colitis. It may also be used for other conditions as determined by your doctor.

Azulfidine is a salicylate. It decreases inflammation. Exactly how it works to treat ulcerative colitis is not known.
Do NOT use Azulfidine if:

* you are allergic to any ingredient in Azulfidine
* you are allergic to salicylates (eg, aspirin) or sulfonamide (eg, sulfamethoxazole)
* you have the blood disorder porphyria or a stomach, bowel, or urinary tract blockage
* you have folate deficiency anemia

Contact your doctor or health care provider right away if any of these apply to you.
Before using Azulfidine:

Some medical conditions may interact with Azulfidine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

* if you are pregnant, planning to become pregnant, or are breast-feeding
* if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
* if you have allergies to medicines, foods, or other substances
* if you have liver or kidney problems, asthma, severe allergies, blood problems (eg, anemia, low white blood cell levels), or rheumatoid arthritis
* if you have glucose-6-phosphate dehydrogenase deficiency
* if you have an infection (eg, strep throat)

Some MEDICINES MAY INTERACT with Azulfidine. Tell your health care provider if you are taking any other medicines, especially any of the following:

* Anticoagulants (eg, warfarin) or methotrexate because the risk of their side effects may be increased by Azulfidine
* Beta-blockers (eg, propranolol), digoxin, or folic acid because their effectiveness may be decreased by Azulfidine
* Methenamine because the risk of crystals in the urine may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Azulfidine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

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